2003 F150 Super Crew 4wd with 132,000. At least half of those miles the truck had a loaded 16' trailer behind it. I even put a plow on the front of it last winter and pushed snow. I've never had any major problems, just normal maintanence. I've changed the tires, brakes, oil, battery and alternator.
I have heard that the front ends start needing a rebuild around 150,000.